Friday, October 18, 2019

Structure of the Legal Profession in the United Kingdom Term Paper

Structure of the Legal Profession in the United Kingdom - Term Paper Example Functionally, the legal profession in the UK is divided into two separate disciplines of barristers and solicitors. In England and Wales, solicitors outnumber barristers eight to one. Solicitors work behind the desk advising and preparing cases for the clients, whereas barristers represent the cases in the courts. Although diverse, the functions of solicitors and barristers are like two sides of the same coin. The basic qualifications necessary for these two branches are the same. It is only after graduation that those wishing to enter the profession as solicitors have to complete a Legal Practice Course according to the requirement of the Law Society, and those choosing to be barristers have to complete Bar Vocational Course franchised by the General Council of the Bar. Both these courses are of one-year duration. (Legal Education in the United Kingdom) Barristers have the right of audience in the Supreme Court and in all other courts, and they specialize in the different area of operations.   Some barristers may specialize in concerning criminal law, while others may be experts in civil cases. Even within the criminal and civil divisions, there may be sub-divisions. For instance, one barrister may specialize in homicidal matters and another may practice on issues concerning fraud, etc. For the ordinary citizen, solicitors are the first point of contact for legal advice and opinion. The solicitors may then advise the litigant on the appropriate barrister who could pursue the case in a court of law. There is yet one more branch of notaries who are small compared to barristers and solicitors. Notaries are authorized to perform functions such as attestations, authentication, administration of oaths, and other legal roles that are not of the litigious nature.   With the complexity of modern times in social, economic, environment and human rights affairs, together with greater awareness of the general citizenry of the legal opportunities available to them, solicitors and barristers have increasing professional challenges. Solicitors and barristers need each other as they perform complementary roles for one another.

Thursday, October 17, 2019

Deforestation in the Amazon Rain Forest Research Paper

Deforestation in the Amazon Rain Forest - Research Paper Example The majority of the rainforest, just over 60 percent, is within Brazil, and the rest of the rainforest falls within the territory of countries such as Peru, Colombia, Venezuela, Ecuador, Bolivia and others (Senna, Costa, & Pires, p. 14). Rainforests once covered over 14 percent of the earth’s surface; however, the same percentage has now decreased to almost 6 percent and the most significant chunk of this deforestation has taken place in the biggest rain forest of Amazon. The deforestation of Amazon Rainforest is perhaps, the most significant concern for green movements, environmental activists, experts, governments, NGOs and various other stakeholders. Human activity and demand in the region has already destroyed a significant portion of rainforest and caused immeasurable damage to the animal species, ecosystem, and the current and future human generations (Rice, p. 25). This paper is an attempt to explore the dynamics of deforestation in the Amazon Rainforest and most import antly, its impact on the soil with respect to soil degradation, soil erosion, and soil leaching. Discussion Prior to the second half of the 20th century, the access to the interior of the rainforest was highly restricted and in the absence of roads, railways and others forms of communication, it was almost irrational to conduct mass deforestation of the Amazon for any purposes (Marshall & Watson, p. 327). The costs of transportation were so high that people did not see deforestation as a profitable venture. However, during the 1960s, many farmers initiated deforestation with the slash and burn method for agricultural purposes. With the creation of roads and railways for transportation and the increasing demand for natural resources, deforestation of the Amazon began at massive rates. The rise on population and the aspirations to become a modern economy further increased the demand for wood and wood products and thus, year after year, rates of deforestation kept increasing. For many years, deforestation within Brazil did not catch the attention of the policymakers of the country as a significant environmental issue because they had evidence to believe that there is a strong link between deforestation and economic growth within the country (Senna, Costa & Pires, p. 14). During the period of 1988-1991, the figures revealed a strong correlation between the slowing down of the economic growth and the decline in the deforestation of the Amazon forest. This correlation was validated by the figures of the period of 1993-1998, when the boom in the economic growth appeared to parallel the increase in deforestation activity of Amazon. Many experts even started claiming this link is not merely a correlation but causation. More importantly, it is a unidirectional causation where deforestation activity within Brazil is causing economic growth and; therefore, it was indispensable (Gabler, Petersen, & Trapasso, p. 89). However, by the mid 2000s, it became apparent to the poli cymakers and the public that the link between deforestation and economic growth is not a significant one. Since then, there has been a significant decline in the deforestation of Amazon. In fact, the rate of deforestation of Amazon in the year 2011 was the lowest during the past couple of decades. Experts believe that many factors have caused this decline. First, during

Questions about election maps Article Example | Topics and Well Written Essays - 250 words

Questions about election maps - Article Example The graphics used usually draw quick attention to the viewer and further provides broader parameters of animation. The other type is called the paper map or the static map and majorly signifies stillness in observation. It is more evident that digital online maps presents modern kind of viewer interaction summarized as follows. They can be updated regularly as opposed to static maps which are printed hence not up to date. Creating online maps have reduced the normal production rate. Consequently static maps involve more paper work during creation stages such that it slows down production process. Digital maps also have the ability to contain more information as large data can be downloaded while the static maps cannot contain large files due to the apparent storage limit. On the other hand static maps are found to be valuable in the sense that they provide vital aspects of the original information stored when effecting new changes. I therefore strongly believe in my opinion that digital online maps are more effective compared to static maps. This is majorly because digital maps have moved with the current trend of technology hence represents the modern face of successful invention with utmost accuracy and

Wednesday, October 16, 2019

Deforestation in the Amazon Rain Forest Research Paper

Deforestation in the Amazon Rain Forest - Research Paper Example The majority of the rainforest, just over 60 percent, is within Brazil, and the rest of the rainforest falls within the territory of countries such as Peru, Colombia, Venezuela, Ecuador, Bolivia and others (Senna, Costa, & Pires, p. 14). Rainforests once covered over 14 percent of the earth’s surface; however, the same percentage has now decreased to almost 6 percent and the most significant chunk of this deforestation has taken place in the biggest rain forest of Amazon. The deforestation of Amazon Rainforest is perhaps, the most significant concern for green movements, environmental activists, experts, governments, NGOs and various other stakeholders. Human activity and demand in the region has already destroyed a significant portion of rainforest and caused immeasurable damage to the animal species, ecosystem, and the current and future human generations (Rice, p. 25). This paper is an attempt to explore the dynamics of deforestation in the Amazon Rainforest and most import antly, its impact on the soil with respect to soil degradation, soil erosion, and soil leaching. Discussion Prior to the second half of the 20th century, the access to the interior of the rainforest was highly restricted and in the absence of roads, railways and others forms of communication, it was almost irrational to conduct mass deforestation of the Amazon for any purposes (Marshall & Watson, p. 327). The costs of transportation were so high that people did not see deforestation as a profitable venture. However, during the 1960s, many farmers initiated deforestation with the slash and burn method for agricultural purposes. With the creation of roads and railways for transportation and the increasing demand for natural resources, deforestation of the Amazon began at massive rates. The rise on population and the aspirations to become a modern economy further increased the demand for wood and wood products and thus, year after year, rates of deforestation kept increasing. For many years, deforestation within Brazil did not catch the attention of the policymakers of the country as a significant environmental issue because they had evidence to believe that there is a strong link between deforestation and economic growth within the country (Senna, Costa & Pires, p. 14). During the period of 1988-1991, the figures revealed a strong correlation between the slowing down of the economic growth and the decline in the deforestation of the Amazon forest. This correlation was validated by the figures of the period of 1993-1998, when the boom in the economic growth appeared to parallel the increase in deforestation activity of Amazon. Many experts even started claiming this link is not merely a correlation but causation. More importantly, it is a unidirectional causation where deforestation activity within Brazil is causing economic growth and; therefore, it was indispensable (Gabler, Petersen, & Trapasso, p. 89). However, by the mid 2000s, it became apparent to the poli cymakers and the public that the link between deforestation and economic growth is not a significant one. Since then, there has been a significant decline in the deforestation of Amazon. In fact, the rate of deforestation of Amazon in the year 2011 was the lowest during the past couple of decades. Experts believe that many factors have caused this decline. First, during

Tuesday, October 15, 2019

Accounting Practical Set Assignment Example | Topics and Well Written Essays - 500 words

Accounting Practical Set - Assignment Example Even if there is profit in the income statement, investors need to look at the cash flow statement to measure actual cash balance of the company. This report will provide an analysis of the cash flow statement and income statement. It will consider why the cash balance has decreased even though a profit has been achieved. This report is based on the information provided by Mr Albert Clarence. The limitation of this project is that it is short time project. Thus detailed analysis will be short. Income Statement might be characterized as a financial statement that measures an organizations financial execution over a particular accounting period. Financial execution is evaluated by giving an outline of how the business acquires its incomes and costs through both working and non-working exercises. It likewise demonstrates the net profit or loss caused over a particular accounting period, normally over a fiscal year or fiscal quarter. Balance Sheet could be characterized as a financial articulation that compresses an organizations liabilities, assets and equity of the shareholders at a particular point in time. These three asset report sections give speculators a thought in respect to what the organization claims and owes, and the sum contributed by the shareholders. Cash flow statement could be characterized as an income or cost stream that changes a cash account over a given period. Cash inflows normally emerge from one of three exercises - financing, operations or contributing - despite the fact that this likewise happens as an after effect of gifts or donations on account of particular fund. Cash outflows result from costs or ventures. This holds valid for both business and any personal account. Accrual Accounting might be characterized as an accounting technique that measures the execution and position of an organization by perceiving various economic occasions paying little respect to

Monday, October 14, 2019

Phage Therapy to Treat Bacterial Infections

Phage Therapy to Treat Bacterial Infections Introduction Bateriophages The word bacteriophage, which is a name for bacterial viruses, means â€Å"eater of bacteria.† These viruses parasitize and kill bacteria. Pioneering work on the genetics of bacteriophages in the middle of the twentieth century formed the foundation of more recent research on tumor-causing viruses and other kinds of animal and plant viruses. In this way bacterial viruses have provided an important model system. A bacteriophage is a bacterial parasite. By itself, a phage can persist, but it cannot replicate except within a bacterial cell. Most phages possess genes encoding a variety of proteins. (Ringo John) Discovery and Significance Bacteriophages, viruses that infect or kill bacteria, were discovered by Frederick W. Twort in England in 1917 independently. Twort observed that bacterial colonies sometimes underwent lysis (dissolved and disappeared) and that this lytic effect could be transmitted from colony to colony. Even high dilutions of material from a lysed colony that had been passed through a bacterial filter could transmit the lytic effect. However, heating the filtrate destroyed its lytic property. From these observations Twort suggested that the lytic agent might be a virus. D’Herelle rediscovered the phenomenon in 1917 (hence the term Twort –d’Herelle phenomenon) and coined the word bacteriophge, which means â€Å"bacteria eater.† He considered the filterable agent to be an invisible microbe- for example, a virus- that was parasitic for bacteria. (Pelczar) Since the bacterial hosts of phages are easily cultivated under controlled conditions, demanding relatively little in terms of time, labor, and space compared with the maintenance of plant and animal hosts, bacteriophages have received considerable attention in viral research. Furthermore, since bacteriophages are the smallest and simplest biological entities known which are capable of self replication, they have been widely used in genetic research. Much has been learned about host parasite relationship from these studies, which have provided a better understanding of plant and animal infections with viral pathogens. Thus the bacterium-bacteriophage interaction has become the model system for the study of viral pathogenicity. (Pelczar) General characteristics Bacterial viruses are widely distributed in nature. Phages exists for most, if not all, bacteria. With the proper techniques these phages can be isoalated quit easily in the laboratory. Bacteriophages, like all viruses, are composed of a nucleic acid core surrounded by a protein coat. Bacterial viruses occurring different shapes, although many have a tail through which they inoculate the host cell with viral nucleic acid. There are two main types of bacterial viruses: lytic, or virulent, and temperate or avirulent. When lytic phages infect cells, the cells respond by producing large numbers of new viruses. That is, at the end of the incubation period the host cell bursts or lyses, releasing new phages to infect other host cells. This is called a lytic cycle. In the temperate type of infection, the result is not so readily apparent. The viral nucleic acid is carried and replicated in the host bacterial cells from one generation to another without any cell lysis. However, temperate phages may spontaneously become virulent at some subsequent generation and lyse the host cells. In addition, there are some filamentous phages which simply â€Å"leak† out of cells without killing them. Types of Bacteriophages There are two types of bacteriophages. Virulent phages and Temperate phages Virulent phages :- As a result of reproduction, virulent phages destroy their host. For example :- T pahges or T1-T7 group of phages infect E.coli bacteria. Temperate Phages :- temperate phages do not kill their host and take over its machinery. For example :- Lambda phage (Study.com) Fig -1 Fates of Phages Morphology and Structure The electron microscope has made it possible to determine the structural characteristics of bacterial viruses. All phages have a nucleic acid core covered by a protein coat, or capsid. The capsid is made up of microbiological subunits called capsomeres. The capsomere consists of a number of protein subunits or molecules called protomers. Figure 1 shows the fine structure and anatomy of a common morphological form of the bacteriophage, one with a head and a tail. Fig. 2 Diagrammatic representation of coliphage Bacterial viruses may be grouped into six morphological types This type has a hexagonal head, a rigid tail with a contractile sheath, and tail fibers. This type has a hexagonal head similar to A. However, it lacks a contractile sheath, its tail is flexible, and it may or may not have tail fibers. This type is characterized by a hexagonal head and a tail shorter than the head. The tail has no contractile sheath and may or may not have tail fibers. This type has a head made up of large capsomeres, but has no tail. This type has a head made up of small capsomeres, but has no tail. This type is filamentous. Types A, B, and C Show a morphology unique to bacteriophages. The morphological types in groups D and E are found in plant and animal viruses as well. The filamentous form of group F is found in some plant viruses. Fig – 3 Types of Bacteriophages Phage Structure Most phages occur in one of two structural forms, having either cubic or helical symmetry. In overall appearance, cubic phages are regular solids or, more specifically, polyhedral; helical phages are rod-shaped. Polyhedral phages are icosahedral in shape. (The icosahedrons is a regular polyhedron with 20 triangular facets and 12 vertices.) This means that the capsid has 20 facets, each of which is an equilateral triangle; these facets come together to form the 12 corners. In the simplest capsid, there is a capsomere at each of the 12 vertices; this capsomere, which is surrounded by five other capsomeres, is termed as a penton. For example, the φX174 exhibits the simple capsid. In larger and more complex capsids, the triangular facets are subdivided into a progressively larger number of equilateral triangles. Thus a capsid maybe composed of capsomeres but it is still based on the simple icosahedrons model. The elongated heads of some tailed phages are derivatives of the icosahedrons. For example the head of the T2 and T4 phages is an icosahedron elongated by one or two extra bands of hexons. Rod-shaped viruses have their capsomeres arranged helically and not in stacked rings. An example is the Bacteriophages M13. Some bacteriophages, such as the T-even coliphages (T2, T4 and T6), have very complex structures, including a head and a tail. They are said to have binal symmetry because each virion has both an icosahedral head and a hollow helical tail. Phage Nucleic Acids Different morphological types of phages are also characterized by having different nucleic acid types. All tailed phages contain double-stranded DNA. The phages with large capsomeres and the filamentous ones have single-stranded DNA. Group E phages have single-stranded RNA. The DNAs of phages are circular under certain conditions. The DNA of phage φX174 is circular both in the virion and in the host cell. The DNA of phage lambda is linear in the virion, but on entering the host cell the cohesive ends join to form a circle. Infection of bacteria by phages Most bacteria are susceptible to attack by bacteriophages. A phage consists of a nucleic acid â€Å"chromosome† (DNA or RNA) surrounded by a coat of protein molecules. Phage types are identified not by species names but by symbols – for example, phageT4, phage lambda, and so forth. During infection, phage attaches to a bacterium and injects its genetic material into the bacterial cytoplasm. The phage genetic information then takes over the machinery of the bacterial cell by turning off the synthesis of bacterial components and redirecting the bacterial synthetic machinery to make phage components. Newly made phage heads are individually stuffed with replicates of the phage chromosome. Ultimately, many phage descendants are made and are released when the bacterial cell wall breaks open. This breaking open process is called lysis. The population of phage progeny is called the phage lysate. Commercial production of Phages In D’Herelle’s laboratory against various bacterial infections five phage preparations were produced. That phage preparations are Bacte-coli-phage, Bacte-rhino-phage, Bacte-intesti phage, Bacte-pyo-phage and Bacte-staphy phage. In the United States therapeutic phages were also produced. Seven phage product for human use produced by the Eli Lilly company in the 1940s including preparations against Staphylococci, Sreptococci, E.coli, and other bacterial pathogen. These preparations contains phage-lysed, bacteriologically sterile broth cultures of the targeted bacteria. These preparations were used against various infections including wounds, vaginitis, acute and chronic infections of the upper respiratory tract, abscesses and mastoid infections. In most of the Western World commercial production of therapeutic phages ceased because of controversy. But in Eastern Europe and in the former Soviet Union the use of phages continued therapeutically together with or instead of antibiotics. (Sulakvelidze.,et.al,2001) Phage therapy Pharmacokinetics Pharmacology is the study of drug’s impact on the body and body’s impact on the drugs. These two concepts are known as pharmacodynamics and pharmacokinetics. In the concept of body, while considering anti microbial as drugs which includes both normal body tissues and the numerous symbiotic micro-organisms. Here we consider only pharmacokinetic aspect of phage therapy pharmacology. Pharmacokinectics describes drug’s potential that are sufficient to achieve primary pharmacodynamic effects. This description is distinguished into absorption, distribution, metabolism and excretion components. Drug movement into the blood is absorption, drug movement into other body tissues is distribution, modification of drugs within the body is metabolism, and movement of drugs out of the body is excretion. These four pharmacokinetic aspects have the effect of both reducing and increasing drug densities. In the case of absorption and distribution, drug densities declines due to drug dilution and at the same time drug density increases in specific body compartments. Metabolism results phage inactivation due to phage interaction with immune systems or â€Å"activation† such as phage in situ replication. Excretion can reduce of drug densities in the body, it can also increased drug densities in bladder with therapeutic benefits. The success of phage therapy depends on generation of sufficient phage densities in the vicinity of the target bacteria to cause bacterial removal from the body at some adequate rate. Sufficient densities of phage will increase either to in situ replication which is a active treatment, or a consequence of what can be described as pharmacologically conventional dosing, is called passive treatment. (Abedon et al,2011) Potential benefits Phage therapy offers a possible alternative to conventional antibiotic treatments for bacterial infections. Phages are very specific to target one or a few strains of bacteria. Traditional antibiotics kill both harmful bacteria and useful bacteria such as those facilitating food digestion. The specificity of phages might reduce the chance that useful bacteria are killed when fighting on infection. Phages have ability to travel to a required site including brain. (Wikipedia.org) Phages are natural antimicrobial agents to fight bacterial infections in humans, in animals or in crops of agricultural importance. Phages have hygiene measure in hospitals and in food production facilities. (Brussow Harald) Alternatives to antibiotics Phage is a viable alternative to antibiotics. The collapse of antibiotics and emergence of harmful and drug resistant bacteria, phage therapy starts again and is being reintroduced. Phage therapy has many potential applications in human medicine, veterinary science and agriculture. Specificity – Phages are more specific than antibiotics, means one phage will only attack and eat one particular bacteria and no other. Each infection needs a particular phage to treat it. To improve the chances of success phage mixtures are applied or samples can be taken and an appropriate phage identified and grown. Phages can be chosen to be indirectly harmless not only to the host organism, but also to other beneficial bacteria, such as gut flora, thus reduce the chances of infections. Phage therapy give rise to few side effects. Phages replicates inside the patient, a smaller effective dose may not even be necessary. Currently phages are used therapeutically to treat bacterial infections that do not respond to conventional antibiotics particularly in Russia and Georgia. (Prof. Kieth) Need to study Phages As we saw research on phages and a lack of knowledge on phage biology affects on clinical failure. The emergence of antibiotics wiped out further research on medical use of phages. After many years, a new problem of bacterial resistance to use of antibiotic has arisen. Bacteria become resistant to drug used in modern medicine by adapting themselves. Problems created in treating patients in hospitals due to the emergence of modified pathogens such as S.aureus, P. aeruginosa, Acinetobacter baumannii and Mycobacterium tuberculosis. Time required to produce new antibiotic is much larger than the time of bacterial adaptation. Therapeutic Uses of Phages and Antibiotics Conclusion For phage therapy multidrug resistant bacteria have opened a second window. (Carlton,1999) Phage therapy is the therapeutic use of lytic phages to treat bacterial infections. It is an alternative to antibiotics developed for clinical use. Phages are more specific than antibiotics that are in clinical use. This therapy is harmless to eukaryotic hosts undergoing therapy and should not affect normal beneficial flora of the host. Theoretically a single small dose is effective. Specificity is the disadvantage because specific phage will only kill a bacterium if it is a match to the specific subspecies. Thus, to improve the chances of success, phage mixture may be applied or clinical samples can be taken and suitable phage identified and grown. In the country of Georgia phages are used to treat bacterial infections therapeutically. (Todar Kenneth)

Sunday, October 13, 2019

Inner Evil Revealed in Film and BBC Productions of Shakespeare’s Richar

Inner Evil Revealed in Film and BBC Productions of Shakespeare’s Richard III   Ã‚  Ã‚   All the passions of the irascible rise from the passions of the concupiscible appetite and terminate in them. For instance, anger rises from sadness, and, having wrought vengeance, terminates in joy. --   St. Thomas Aquinas   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   In Richard III, Shakespeare creates evil personified.   The wicked protagonist conspires against kin, plots political takeovers, woos widows, sets assassins against children, and relishes each nefarious act.   We watch Richard's bravado with wicked glee and delight in each boasting comment sent our direction.   Once the bad guy becomes seductive, even amusing, in his blatant cruelty, the playwright must intervene to counterbalance his own brilliant wit.   But how can this devil Richard be brought to his knees with the appropriate high style demanded by the script's momentum?   Shakespeare leaves us the briefest of stage direction: "Alarum. Enter Richard and Richmond; they fight; Richard is slain" (V.v.).   Once "the bloody dog is dead," Richmond prays for "smooth-faced peace" (V.v.2,33).   So soon after Richard's tormented dream of accusing ghosts, this closing scene enforces a mood described by Robert Ornstein as "one of somber reflection, not of joyous celebration" (263).   However, the interpretive liberties taken by three twentieth-century filmmakers establish elaborated messages about the horrors of bloodshed, the inevitability of power struggles, and the mythmaking of villains.   Ã‚  Ã‚  Ã‚  Ã‚  Ã‚   The 1982 BBC production takes the audience through a series of reactions: the bloodthirst for revenge, the prayer for redemption, and the vision of hellish destruction.   We watch Richard circled by soldiers, baited like a bea... ...thin this structure, his body will pull him downward with the mocking demands of its physical being" (35).   Structurally, the gargoyles often function as gutter drains, spewing forth wastewater to protect the aesthetics of the church.   Similarly, Richard epitomizes our hatreds and cruelties, reminding us of the evil inside; whether he cleanses our sins through his death depends on the director's approach to redemption and transference. Works Cited Eccles, Mark.   "Richard III on Stage and Screen." Richard III.   New York: Signet Classic, 1988.   265-78. Hallett, Charles A. and Elaine S. Hallett.   The Revenger's Madness.   Lincoln: U of Nebraska P, 1980.   (Epigraph) Ornstein, Richard.   "Richard III."   Richard III.   New York: Signet Classic, 1988.   239-264. Spivack, Charlotte.   The Comedy of Evil on Shakespeare's Stage.   London: Associated UPs, 1978.